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Generic Imuran (Azathioprine) Information
When is Generic Imuran (Azathioprine) indicated for use?
Azathioprine belongs to a group of medications known as immunosuppressants and it is used when you have had an organ transplant and you need a medication that will prevent your body from rejecting the new organ, in most cases a kidney. It is a purine analogue immunosuppressant and it works in such a way that it lowers the levels of white blood cells in your bone marrow, thus reducing the activity of your immune system. While this prevents the rejection of a transplanted organ, it also makes your body more vulnerable to infections and that is why you need to make sure you reduce the risk of being exposed to infections to a minimum. Besides this use with patients who have had organ transplantations, Azathioprine can also be used in treatment of different autoimmune diseases, like for example restrictive lung disease, myasthenia gravis, autoimmune hepatitis, inflammatory bowel diseases, rheumatoid arthritis, neuromyelitis optica, atopic dermatitis, multiple sclerosis and pemphigus. Depending on the treatment being treated, Azathioprine can be used both alone and in conjunction with other immunosuppressants.
Discussing Generic Imuran (Azathioprine) with your doctor
As Azathioprine can lead to some very serious unwanted side effects, you need to discuss your medical history and your present medical condition with your doctor in order to benefit the most from your Azathioprine treatment. The most important fact that you must not fail to mention is any allergy to Azathioprine, in which case, your doctor will most likely want you to look for an alternative treatment. Also, if you have taken or if you are taking certain alkylating cancer medications, such as Chlorambucil, melphalan or cyclophosphamide, you need to tell your doctor about it, as otherwise you will be in greater risk of contracting cancer in the future. Furthermore, some conditions may be made worse by the Azathioprine treatment and your doctor will want to run additional tests to make sure you can safely use this medications. Among these conditions, you will find: TPMT deficiency, any type of cancer, blood disorders, kidney disease, active infections, decreased function of the bone marrow and liver disease.
Is Generic Imuran (Azathioprine) indicated for pregnant women?
It is likely that Azathioprine will have adverse effects on the health of your child and if you are pregnant, you need to tell this to your health care provider, who will then outweigh the risks against the possible benefits. On the other hand, if you have started your Azathioprine treatment and you do become pregnant; your doctor will most likely want you to continue your treatment nonetheless. However, breastfeeding women will in majority of cases be told to refrain from taking Azathioprine as it passes into breast milk and poses a risk to the health of the nursing child.
How to properly use Generic Imuran (Azathioprine)?
Azathioprine is an oral drug and it is taken either once or twice every day, depending on numerous factors. Among the factors that will decide about the proper dosage and the duration of your treatment are such like weight, your medical condition, as well as the way your body responds to the treatment. In addition to these, the condition for which the medication was indicated also has an effect on the dosage, which in turn needs to be adhered to by the patient. If you discover that Azathioprine upsets your stomach, you should take it with your meals. Some people decide on their own to stop using Azathioprine because they think it hasn't got any effects on their condition. You should never do the same, as it sometimes takes up to a couple of months for this drug to start working, like for example in the case of arthritis. If it is possible, you should take the medication at the same time every day to ensure the same level of the drug in your system. Also, if your doctor tells you to take blood tests, keep the appointments.
Which side-effects can be caused by Generic Imuran (Azathioprine)?
In most cases, side effects of Azathioprine are only minor and they include nausea, diarrhea, vomiting and muscle aches. These will most likely go away on their own. However, if you do feel any of the much rarer but more serious side effects of Azathioprine, you need to tell your doctor about them as soon as possible. These include: lack of energy, pain in your upper stomach, flu-like symptoms, blurred vision, chills, sore throat, weakness, fast heartbeat, confusion, pale skin, mouth sores, loss of appetite, jaundice, rash, stomach pain, fever, shortness of breath, difficulties sleeping, dizziness, headaches, unusual bruising and bleeding.
Which medications might interact with Generic Imuran (Azathioprine)?
This is the list of medications that are the most common interactions with Azathioprine: alkylating cancer drugs, ACE inhibitors, allopurinol, aminosalicylates, blood thinners, chemotherapy drugs, medications that have an effect on your bone marrow.
What to do in case of a Generic Imuran (Azathioprine) overdose?
If you think that you have ingested too much Azathioprine, you need to seek emergency medical help and tell them about any symptoms of an overdose that might include nausea, diarrhea, vomiting, sore throat and especially any signs of infection.
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