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Sibutramine Information
Sibutramine Overview for Patients
Sibutramine is a type of appetite-suppressing drug which is used for promoting and maintaining weight loss. It is most commonly known by its trade name of Meridia though Sibutramine is also available under other names and in its generic form. Additionally, Sibutramine may be an ingredient in many weight-loss formulations. Sibutramine is no longer available in many markets pending the results of further studies into the drug's safety.
Sibutramine Indications
Sibutramine can be used for promoting weight loss through appetite suppression as well as helping patients maintain weight that they have lost. Sibutramine should only be used along with other methods of weight loss and weight-loss maintenance such as eating a healthy diet and lifestyle changes. Sibutramine should only be used by patients who are/were obese or have health problems due to being overweight (such as hypertension or diabetes).
How is Sibutramine Used?
Sibutramine is taken in oral form in order to suppress appetite. Typically, it is taken once per day at the same time every day. You may take Sibutramine without regards to meals. The dosage amount of Sibutramine is usually 10 mg daily but this amount may be reduced to 5 mg or increased to 15 mg. It is advised against taking more than 15 mg of Sibutramine daily.
Sibutramine Efficacy
In clinical trials, Sibutramine was very effective in promoting weight loss when it was combined with a low-calorie diet. More than half of the trial patients lost a minimum of 4 lbs during the first month of treatment and 5% of their starting body weight within 6-12 months. However, the study also showed that Sibutramine may not be effective in everyone. 80% of the patients who lost less than 4 lbs during the first month were not able to successfully lose substantial weight within 6-12 months. Thus, if you do not lose 4 lbs after 1 month of treatment with Sibutramine, your doctor may decide to discontinue treatment.
Sibutramine Warning
While Sibutramine was initially considered safe for promoting and maintaining weight loss, a recent study shows that the drug may pose risk of serious heart problems including fatality. Some of the possible risks of Sibutramine may include heart failure, strokes, heart attack, or fatality. Because of these risks, Sibutramine has been removed from the market by request of various health organizations including the FDA and Health Canada. If you are currently using Sibutramine, you should talk to your doctor about finding a safer treatment option.
Sibutramine Availability
As of 2010, Sibutramine has been removed from the market in many nations including: the US, UK, European Union countries, Canada, Australia, Mexico, India, Hong Kong, China, and Thailand. Sibutramine is still available from some manufacturers, particularly in Asian countries. It is possible to buy generic Sibutramine online through these foreign pharmacies. However, note that it may be illegal for you to import Sibutramine to your place of residence.
How Does Sibutramine Work?
Sibutramine works in a very similar way to antidepressant medicines. In our brains, neurotransmitters are constantly being released to carry chemical messages. After being relayed, the neurotransmitters are quickly absorbed back into their source. Sibutramine inhibits the way that the neurotransmitters are reabsorbed. While this is the same mechanism of action as antidepressants, Sibutramine is more effective in the part of the brain responsible for satiety rather than unbalanced moods.
Sibutramine Side Effects
It is common for patients using Sibutramine to have their unserious side effects: dried mouth, increased appetite, dyspepsia, unusual tastes in mouth, constipation, insomnia, tiredness, pains during menstruation, headache, flushing, or musculoskeletal pains. Let your doctor know if these side effects continue or become worse. If you have any of these unlikely but possibly serious side effects while using Sibutramine, immediately get medical attention: changes to heart rate, unusual moods/behaviors, seizure, urinating difficulties, becoming bruised easily, unusual bleeding, skin/eye whites become yellowish, angina, unusual fever, changes to eyesight, rigors, tingly feeling, tarry feces, vomiting blood, shortness of breath, edema, shakiness during fever, or signs of allergic reaction. This is not a full list of side effects. Talk to your doctor for more information.
Sibutramine Brand Names
Before it was withdrawn from the market, Sibutramine was available under various brand names. Some of these include: Meridia, Reductil, and Sibutrex. Additionally, Sibutramine was available as an ingredient in weight-loss drugs such as Fruta Planta. Sibutramine was also available in many generic forms. There is no difference between generic Sibutramine and the brand-name forms in terms of efficacy. However, the dosing or administration instructions may differ and they may contain different inactive ingredients.
Sibutramine Contraindications
Sibutramine should never be taken by anyone: under 16 years old, over 65 years old, pregnant, breastfeeding, bulimic, anorexic, with cardiovascular problems, or with a history of stroke. Additionally, it may not be safe for you to take Sibutramine if you have any of these health problems: hypertension, chest pain, diabetes, glaucoma, hypothyroidism, hepatic disease, renal disease, gallstones, seizures, bleeding problems, mental health problems, or current/past drug addiction.