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Sildenafil Citrate Information
Sildenafil Citrate Overview for Patients
Sildenafil Citrate is a male impotence treatment which is more commonly known by its brand name of Viagra. It was first made available in 1998, thus making it the first FDA approved drug for treating impotence. Since its release, Sildenafil Citrate has been used by more than 20 million men worldwide. Even with the approval of two new drugs for treating impotence (Tadalafil and Vardenafil), Sildenafil Citrate still remains a popular treatment choice. The original patent on Sildenafil Citrate was held by the group Pfizer. It has since expired in many countries thus making the drug available in generic forms worldwide.
Sildenafil Citrate Indications
Sildenafil Citrate was originally made as a treatment for the condition pulmonary arterial hypertension. It was soon discovered that the drug was also effective as a treatment for male impotence. Additionally, Sildenafil Citrate may be effective for treating altitude sickness though it is not currently approved for this use.
How does Sildenafil Citrate Work?
Sildenafil Citrate belongs to a group of drugs called PDE5 inhibitors. When sexual stimulation occurs in a male, a series of chemical reactions take place in order for erection to occur. Part of the process involves the chemical GMP relaxing penile muscle tissues and allowing blood to flow into spongy tissues. GMP is degraded by an enzyme called phosphodiesterase type 5, or PDE5. When patients take Sildenafil Citrate, the actions of PDE5 are blocked. This allows penis muscles to remain relaxed and blood to flow to the penis. Sildenafil Citrate will thus help men achieve erections and make erections longer lasting and firmer. The medicine will not cause an erection without a male first being sexually stimulated nor will it increase libido. For treating pulmonary arterial hypertension, Sildenafil Citrate works by relaxing arterial walls and thus decreasing blood pressure.
Sildenafil Citrate Dosage
Dosage of Sildenafil Citrate should be determined by a doctor based on your specific condition and other factors including response to treatment. For treating male impotence, the standard dosage of Sildenafil Citrate is 50 mg taken on an as-needed basis about 60 minutes before anticipated sexual relations. This dosage amount may be decreased to 25 mg or increased to a maximum of 100 mg. For treating pulmonary arterial hypertension, Sildenafil Citrate is typically taken in dosages of 20 mg three times per day. Dosages should be taken with at least 4-6 hours between them. Sildenafil Citrate may be taken without regards to meals.
Is Sildenafil Citrate Safe?
Studies have shown that Sildenafil Citrate is safe for healthy adult patients, including geriatrics. Patients with certain health risk factors, however, may not be able to take Sildenafil Citrate or may need to follow special instructions during treatment. Do not use Sildenafil Citrate without first telling your health care provider of your full medical report, particularly of these conditions which may be contraindicated: history or priapism, penis formations/scarring/curvatures, hypertension, hypotension, ocular problems, cardiovascular problems, renal impairment, hepatic disease, pulmonary edema, or have recently had a stroke. It also may not be safe to use Sildenafil Citrate before having certain medical operations so be sure your doctor/dentist knows you are taking this medicine beforehand.
Sildenafil Citrate and Women Patients
Sildenafil Citrate is not indicated for use in female patients. It will not help women become sexually stimulated and its efficacy in treating pulmonary arterial hypertension in females is not clearly researched. Females should never take Sildenafil Citrate unless they have specifically been told to do so by their health care providers.
What Side Effects Occur from Sildenafil Citrate?
Many patients taking Sildenafil Citrate do not experience any adverse effects. However, the following unserious adverse effects could occur: vertigo, feeling lightheaded, headaches, hot/tingly feeling, acid reflux, bloody nose, insomnia, or inflammation to limb extremities. You may also experience some mild changes to your eyesight such as becoming more sensitive to light or partial color blindness. Let your doctor know if any of these effects are severe or continue. Sildenafil Citrate has in rare cases caused a sudden blindness in patients. If this happens, immediately get medical attention. Sildenafil Citrate may also cause hearing problems. If your hearing changes at any point during treatment, tell your doctor at once. Do this even if you think the hearing loss is not serious. Uncommonly, Sildenafil Citrate has caused men to get long-lasting erections which may be painful. This is not normal and could lead to permanent penile damage. Get immediate medical help if your erection lasts more than 4 hours or hurts.
What You Should Know before taking Sildenafil Citrate
Sildenafil Citrate could put extra stress on your heart. This is normally not dangerous by itself. However, if it is combined with additional cardiovascular exertion (such as can happen during sexual activity), serious health problems could occur. You should stop all activity and get medical help if you have any unusual side effects during sexual activity such as: fainting, chest pain, pain/numbness on one side, jaw pain, or vertigo.
Overdose of Sildenafil Citrate
Do not ever take more Sildenafil Citrate than you have been prescribed as a serious overdose could occur. Some of the signs of Sildenafil Citrate overdose may include: extreme vertigo, loss of consciousness, or priapism. Get medical help at once or call your area's poison control helpline if you think an overdose has occurred.