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Tadalafil Information
Tadalafil Overview for Patients
Tadalafil is a type of PDE5 inhibitor which is commonly known by its brand name of Cialis. It is indicated for treating male impotence as well as pulmonary arterial hypertension. Tadalafil gained approval from the FDA in 2003, thus making it the third drug of its kind to get approval for treating impotence (the first two were Sildenafil Citrate and Vardenafil).
How Does Tadalafil Work?
Tadalafil hinders the actions of an enzyme called phosphodiesterase type 5, usually shortened to PDE5. This enzyme is responsible for triggering the chemical messenger GMP which causes certain muscles to contract, including those of the penis's soft tissues. When Tadalafil is taken, PDE5 is inhibited and muscles remain relaxed. This allows more blood to flow to the penis for a longer time, causing erections to occur from sexual stimulation and making erections become firmer and longer lasting. Tadalafil will also keep lung arteries relaxed, thus reducing pulmonary arterial high blood pressure.
Is Tadalafil Available in Generic Form?
Tadalafil is available under the brand names of Cialis (for treating male impotence) and Adcirca (for treating pulmonary arterial hypertension). However, there are many other brand names of Tadalafil from various manufacturers as well as generic Tadalafil forms available. Generic Tadalafil is the same as the brand name forms in terms of active ingredient, mechanism of action, side effects, and precautions. However, it must be noted that generic Tadalafil may come in different dosages than you are used to and may have different usage instructions. Make sure you always buy the proper dosage of generic Tadalafil as you have been prescribed and read the patient usage information before taking the medicine.
How to take Tadalafil
For treating male impotence, Tadalafil is usually taken on an as-needed basis about 1 hour before sexual activity. The standard dosage strength of Tadalafil for male impotence is 10 mg. This amount may need to be lowered for patients with impairments, the elderly, or patients who are sensitive to its effects. Dosage can be increased to a maximum of 20 mg. No more than 1 dosage of Tadalafil should be taken in a period of 24 hours. For treating pulmonary arterial hypertension, Tadalafil is taken on a daily basis, usually in dosages of 40 mg taken once per day. Tadalafil can be taken with or without foods. Always take Tadalafil precisely as it was prescribed to you by a doctor.
Do You Need a Prescription for Tadalafil?
In most nations, Tadalafil is available with a standard doctor's prescription. However, some countries sell Tadalafil as an over-the-counter drug without a prescription. It is possible to purchase Tadalafil without a prescription through many online pharmacies. Note, however, that it may be illegal for you to import prescription drugs to your area of residence. Even if you are able to buy Tadalafil without a prescription where you live, it is still best to consult a doctor to make sure that this treatment is right for you.
Who Should Take Tadalafil?
Tadalafil is generally considered safe for all healthy adult males to take, including geriatric patients who have been told they may safely engage in sexual activities. However, Tadalafil may not be the best treatment choice for everyone. It is possible that erectile dysfunction could be caused by a serious underlying condition. Before using Tadalafil for treating erectile dysfunction, it is best first to discuss with your doctor what could be causing your condition and the best ways to treat it.
Tadalafil Contraindications
Tadalafil may not be safe for you to take if you have certain health risk factors. Before you use Tadalafil, you should make sure that your doctor is aware of your full medical history, particularly these conditions which may be contradicted for the medicine: hypotension, renal impairment, hepatic disease, cardiovascular problems, recent strokes/heart attacks, disorders involving blood cells or bleeding, ocular problems, penile deformities, ulcers, or have been advised against having sexual activities due to health risks.
Common Tadalafil Side Effects
Patients using Tadalafil may experience some unserious side effects. These are usually mild and may include: a warm feeling in your body, cold-like symptoms, headaches, forgetfulness, dyspepsia, diarrhea, muscular pains, or backache. You should inform your doctor if these side effects are severe or continuous. You may need to have your dosage of Tadalafil adjusted.
Possible Serious Tadalafil Side Effects
Most men using Tadalafil do not have serious side effects. However, it is possible for Tadalafil to cause serious health problems including priapism, sudden blindness, and hearing problems. Tadalafil should not cause abnormally long-lasting erections (more than 4 hours) or painful erections. If this happens, immediately seek emergency medical treatment as severe chronic harm could occur. There have been incidences of Tadalafil users suddenly becoming blind. Get emergency medical attention at once if this happens. Tadalafil may lead to deafness. Often, the symptoms of this problem go ignored by patients as they think it is a normal part of aging. Immediately report any changes to hearing to your doctor.
Warning about taking Tadalafil
Tadalafil can affect your heart and cause extra strain on it. When this is combined with physical exertion, it can lead to serious cardiovascular events. If you have any of these symptoms during physical activity while taking Tadalafil (including during sexual activities), you should immediately stop what you are doing and get medical help: severe faintness, seizures, breathlessness, inflammation to hands/feet/legs, or chest pain which may radiate outwards.