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Vardenafil Information
Vardenafil Overview for Patients
Vardenafil is a type of medicine which is used for treating male impotence in which men cannot achieve or maintain erection. It is commonly known by its brand name of Levitra or Staxyn. Vardenafil was approved by the FDA in 2003 making it the second approved treatment for male impotence after Sildenafil Citrate.
How Does Vardenafil Work?
When sexual stimulation occurs in males, a chemical reaction takes place in the body. Part of this reaction involves chemical messenger GMB causing penis muscles to relax and blood to flow into the penis's spongy tissues. However, this process can be hindered by a naturally-occurring enzyme called phosphodiesterase type 5 (or PDE5). Vardenafil, as well as other approved drugs for treating male impotence, work by inhibiting PDE5. This allows penile muscles to remain relaxed so erection can occur. Achieved erections will also be maintained longer and be firmer. Because the entire chemical reaction which causes erection is triggered by sexual stimulation, Vardenafil will not cause erection without sexual stimulation.
Vardenafil Dosage and Use
Under the brand name of Levitra, Vardenafil is usually taken in dosages of 10 mg about 1 hour before having sexual relations. This dosage can be decreased to 5 mg or increased to a maximum of 20 mg. Patients with certain impairments or who are sensitive to the drug's effects may require low starting dosages. Levitra tablets should be swallowed whole and may be taken without regards to meals. Under the brand name of Staxyn, Vardenafil is taken as a 10 mg disintegrating tablet about 1 hour before sexual relations. The tablet must be put on the tongue and allowed to fully disintegrate. It should never be swallowed whole. Do not take disintegrating forms of Vardenafil with liquids though they can be taken without regards to meals.
Is Generic Vardenafil Available?
Vardenafil is currently made by Bayer HealthCare Pharmaceuticals, promoted by GlaxoSmithKline and dispensed by Schering Corporation. The drug is under patent protection which means that it is illegal for different companies to manufacture the medicine. The patent for Vardenafil does not expire until 2018 thus no approved generic forms of the medicine will be on the market before then. However, many companies (particularly in Asia and Latin America) are contesting the patent rights to the drug by making generic Vardenafil. These forms of generic Vardenafil can be purchased (usually online) for a much lower price than the brand name forms. However, it must be noted that they are not FDA approved and may contain inferior quality ingredients.
What is the Difference between Vardenafil and Generic Levitra?
Vardenafil is simply the name for Levitra's active ingredient. Many people mistakenly call a medicine's active ingredient its "generic name." However, a generic drug is actually a form of the active ingredient which has been made by another company. As Vardenafil is still protected by patent rights, there are no (approved) forms of generic Levitra available.
Vardenafil Formulations
Vardenafil is available in oral tablet from under the name of Levitra. These tablets come in dosage strengths of 2.5 mg, 5 mg, 10 mg, and 20 mg. Note that the 2.5 mg dosage strength may not be available in all areas. Vardenafil also comes as disintegrating tablets under the name of Staxyn. This form of the medicine only comes in 10 mg tablets which are supplied in blister packaging.
Side Effects of Vardenafil
It is common for patients to experience these unserious side effects while using Vardenafil: a hot/tingly feeling, headache, dyspepsia, cold-like symptoms, vertigo, or nausea. Patients may also have some mild changes to their vision such as light sensitivity or color-perception impairment. Let your doctor know if these effects are severe or worsen. Vardenafil could in rare cases could cause a condition called NAION in which blindness suddenly occurs. Get emergency medical help if this happens. Vardenafil should not cause priapism, a condition in which erections last for over 4 hours or are painful. Immediately seek emergency medical treatment if this occurs. You should let your doctor know at once if you have any of these side effects from Vardenafil which could be serious: changes to heart rate, convulsions, or amnesia.
Cautions while taking Vardenafil
Engaging in sexual activity can put stress on your cardiovascular system. When this is combined with the effects of Vardenafil, the chances of a serious cardiovascular event occurring are increased. If you have any of these symptoms during sexual activity while taking Vardenafil, you should stop all activity and get medical attention at once: fainting, becoming very dizzy, or pains in chest.
Vardenafil Contraindications
Do not use Vardenafil without first informing your health care provider about your complete medical history. It may not be safe for you to take Vardenafil, particularly if you have these problems: ocular problems, hypotension, penile deformations, have had priapism, anemia, cancer, hepatic or renal disease, cardiovascular problems, have recently had a stroke, or extreme hypertension.
Interactions with Vardenafil
Never take Vardenafil with nitrate type drugs as a serious or life-threatening interaction could occur. These drugs are often used for treating angina and other heart conditions. Nitrate may also include certain recreational drugs which are inhaled. Other drugs, including natural products and over-the-counter medicines, may interact with Vardenafil so do not take this medicine without first telling your health care provider of all drugs you use.