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Wellbutrin Information
Wellbutrin Information for Patients
Wellbutrin is a type of antidepressant medicine which is indicated for treating depression. While the brand-name drug Wellbutrin is only indicated for this purpose, its active ingredient Bupropion is also approved for aiding in smoking cessation and treating seasonal affective disorder. There is also evidence that Wellbutrin is effective in treating sexual dysfunction, obesity and ADHD, though it is not approved for these conditions.
How to take Wellbutrin
Wellbutrin is typically taken 1-3 times per day as oral tablets. Unless you have been directed otherwise, you may take Wellbutrin without regards to meals. It is common for doctors to initiate treatment with Wellbutrin at low dosages then increase this dosage gradually. Increases in Wellbutrin dosage are never to be greater than 100 mg over a 3-day period of time. For example, a patient may take 100 mg of Wellbutrin twice per day for the first three days of treatment. Then, on the fourth day, dosage may be increased to 100 mg taken 3 times per day. This helps prevent side effects such as seizure. The maximum daily dosage of Wellbutrin is 450 mg daily. Wellbutrin Extended-Release should always be swallowed whole and never chewed, crushed, or broken in any way.
Wellbutrin vs. Wellbutrin SR and Wellbutrin XR
When Wellbutrin is labeled simply as "Wellbutrin," it is the immediate-release form of the medicine. This form typically must be taken 3 times per day. Wellbutrin SR is the sustained-release form of the drug. This should not be confused with Wellbutrin XR, which is the extended release form of the drug. While it is common to use the terms "sustained release" and "extended release" interchangeably, they are not the same when it comes to Wellbutrin. Wellbutrin SR is released faster than Wellbutrin XR. Thus, Wellbutrin SR is typically taken twice per day whereas Wellbutrin XR is taken once per day.
Is Generic Wellbutrin Available?
After the patent for Wellbutrin expired, many generic forms of the drug became available on the international market. Generic Wellbutrin can be purchased at a substantially less cost than the brand-name version. In approved forms of generic Wellbutrin, there is no difference compared to the brand-name form in terms of efficacy, side effects, interactions, and precautions. However, patients should be sure that they are purchasing approved forms of generic Wellbutrin so not to buy substandard forms of the drug. Also, note that some countries (including Canada) only have Wellbutrin SR in generic form.
Warning about taking Wellbutrin
Recently studies have shown that taking antidepressant drugs such as Wellbutrin can, in rare cases, actually cause depression to worsen. These same studies show that there may be a higher incidence of suicide occurring when depressed patients take an antidepressant. This is more likely if the patient is under the age of 25. Before taking Wellbutrin, you should talk to your doctor about the risks of taking antidepressants. If at any point during treatment your condition worsens or you have symptoms of a new mental health disorder, immediately contact your health care provider.
Side Effects of Wellbutrin
When first starting treatment with Wellbutrin, it is common for patients to have some unserious side effects including: dyspepsia, lack of saliva, headaches, infrequent bowel movements, increase of perspiration, joint pains, cold-like symptoms, blurry vision, unusual tastes in mouth, or vertigo. Let your health care provider know if these effects are continuous or worsen. In the unlikely to rare event that you have any of these serious adverse effects from Wellbutrin, immediately contact your health care provider: angina, loss of conscious, changes to heart rate, changes to hearing, migraine, unusual moods/behaviors, tremors, changes to weight, muscular pains, or changes to urination (including painful urination). Get immediate medical attention if you have a seizure or allergic reaction from Wellbutrin.
Who Should Not Use Wellbutrin?
Wellbutrin may not be the right treatment choice for you if you have certain health risk factors. Do not take this medicine without first informing your health care provider of your full medical report. The following conditions may be contraindicated for Wellbutrin: allergies, drug withdrawal, conditions causing seizures, current/past drug addiction, brain problems, head injuries, are diabetic, hypertension, renal impairment, hepatic problems, or personal/family history of manic depression/suicide.
Wellbutrin during Pregnancy and Breastfeeding
Wellbutrin can cause adverse health effects to an unborn child if it is taken during pregnancy, particularly during the last trimester. However, depression is an illness which should not be untreated. If you are pregnant, make sure your doctor knows before you start using Wellbutrin. If you become pregnant during treatment, do not stop taking Wellbutrin without first talking to your doctor. It is advised against breastfeeding while taking Wellbutrin as it can get passed into breast milk and have adverse effects on a nursing child.
Wellbutrin Interactions
Do not take Wellbutrin without first telling your health care provider of all drugs (including natural substances, illicit drugs and over-the-counter treatments) that you use. A serious interaction could occur. These are just some of the drugs which may interact with Wellbutrin: drugs affecting serotonin and other neurotransmitters (psychiatric drugs, MDMA, LSD, or MAO inhibitors), antiviral drugs, anticonvulsants, diabetes treatments, x-ray dye, anti-smoking treatments, sedating drugs, narcotics, stimulating drugs (including cocaine, amphetamines and many weight-loss drugs), and blood thinners.